基于中医汤剂的中药常用剂量研究进展

Research Progress on Usual Dosage of Herbs in Traditional Chinese Medicine Decoction

药物剂量与临床疗效密切相关,中医素有＂不传之秘在于量＂的说法。药物的现代临床剂量与古代医籍中剂量之间存在较大的差异,按照古医籍超剂量使用时,有屡获良效的报道,亦有毒副反应的报道。本文拟总结中医汤剂方药剂量标准存在的问题及超剂量使用引发的争议;同时,从中医临床经验、现代文献、古代文献及现代中医药实验研究等方面综述了中药剂量研究的各种方法,并对各种方法进行了分析和展望;以阐述中药剂量是中医传承和发展过程中亟待解决的关键问题和重要问题。

Dosage is closely related to clinical efficacy. Traditional Chinese medicine（TCM） is known as the secret of no impartment is the dose. There is a great difference between the modern clinical dose and the dose in the ancient medical books,and it has been reported many cases of good results by using overdose of drug according to the ancient medical books,and there are also reports of toxic and side effects. This paper summarizes the problems caused by the dosage standard of TCM and the disputes arising from the use of overdose. At the same time,the paper summarizes the research method of TCM dose from clinical experience,Chinese modern literature,ancient literature and modern Chinese medicine experimental research, and analyzes and prospects various methods,and expounds that the dose is the key and important problem to be solved in the inheritance and development of TCM.