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季铵盐与热力协同杀灭细菌芽孢研究 被引量:3

Study on synergistic sporicidal efficacy of quaternary ammonium compound and heat
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摘要 目的研究3种长链季铵盐消毒液与热力协同作用对细菌芽孢杀灭效果,同时观察复配后是否有增效作用。方法在不同温度条件下,采用悬液定量杀灭试验方法研究季铵盐单方和复配消毒液对枯草杆菌黑色变种芽孢的杀灭效果。结果 80℃作用3 h,3种单方季铵盐对细菌芽孢杀灭对数值分别为3.87、5.64和6.12。以1∶1∶1比例复配后的季铵盐消毒液在20℃和40℃时对枯草杆菌黑色变种芽孢作用3 h杀灭对数值均<0.5;60℃时为2.73;80℃时为4.84。结论热力对单方和复方季铵盐消毒液有增效作用,3种季铵盐复配后杀菌效果反而下降。 Objective To study the sporicidal efficacy of three kinds of long-chain quaternary ammonium disinfectant under the heat,and to observe whether there was a synergistic effect after compounding the three kinds of disinfectant above at the same time. Method Suspension quantitative germicidal test was used to observe the efficacy of the three simple disinfectants and the compound disinfectant to spores of Bacillus subtilis var. niger under different temperature. Results The killing logarithm value of spores of Bacillus subtilis var. niger exposed to the three simple ammonium disinfectants was 3. 87,5. 64 and 6. 12 respectively after being treated at 80 ℃ for 3 h. It were both 0. 5 when exposed to the compound ammonium disinfectant( compounding the three simple ammonium disinfectants above in the ratio of 1 ∶ 1 ∶ 1) after being treated at 20 ℃ and 40 ℃ for 3 h. It was 2. 73 at 60 ℃ and 4. 84 at 80℃. Conclusion Effect was enhanced for the simple ammonium disinfectants and the compound quaternary ammonium disinfectant as temperatures rise. Germicidal efficacy declined after mixing the three simple ammonium disinfectants.
作者 蒋邱逃 吴晓松 陈越英 JIANG Qiu - tao;WU Xiao - song;CHEN Yue - ying(Wuhou District Center for Diseases Control and Prevention,Chengdu Sichuan 610041;1 Jiangsu Provincial Center for Disease Control and Prevention, Chin)
出处 《中国消毒学杂志》 北大核心 2017年第12期1100-1101,1104,共3页 Chinese Journal of Disinfection
关键词 季铵盐消毒剂 热力 协同作用 枯草杆菌黑色变种芽孢 quaternary ammonium compound temperature synergistic e[)~cacy spores of Bacillus subtilis var. niger
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