肝硬化和肝源性糖尿病临床关系分析

Analysis of Clinical Correlation between the Cirrhosis and Hepatic Diabetes

目的探讨肝硬化和肝源性糖尿病的临床关系。方法选取2016年度该院收治的45例肝硬化合并糖尿病患者作为研究组,同时选取同期收治的45例肝硬化未合并糖尿病患者作为对照组,并比较不同组患者肝功能分级、临床表现和并发症。结果研究组患者出现多饮多食多尿的现象明显高于对照组(P<0.05),研究组患者恶心呕吐、黑便、腹水、腹胀、脾肿大和乏力等现象与对照组患者比较差异无统计学意义(P>0.05);研究组患者肝功能A级明显低于对照组(P<0.05),肝功能B级患者者明显高于对照组(P<0.05),但肝功能C级两者差异无统计学意义(P>0.05);研究组患者自发性腹膜炎、肝肾综合征和肝性脑病发生率均明显高于对照组(P<0.05)。结论肝源性糖尿病与肝硬化疾病具有密切相关性,肝硬化合并肝源性糖尿病患者其临床症状表现多样且复杂,临床上需对原发疾病进行积极治疗,同时严格控制血糖水平。

Objective To study the clinical correlation between the cirrhosis and hepatic diabetes. Methods 45 cases of patients with cirrhosis and hepatic diabetes admitted and treated in our hospital in 2016 were selected as the research group, while 45 cases of patients with cirrhosis without hepatic diabetes in our hospital at the same period were selected as the control group, and the liver function classification, clinical performance and complications were compared between the two groups. Results The occurrence of polydipsia and polyuria in the research group was obviously higher than that in the control group（P0.05）, and the differences in the nausea and vomiting, melena, ascites, abdominal distension, splenomegaly and fatigue between the two groups were not obvious（P0.05）, and the liver function A level was obviously lower than that in the control group（P0.05）, and the patients with liver function B level was obviously higher than that in the control group（P0.05）, but the difference in the number of patients with liver function C level between the two groups was not obvious（P0.05）, and the incidence rates of spontaneous peritonitis, hepatorenal syndrome and hepatic encephalopathy in the research group were obviously higher than those in the control group（P0.05）. Conclusion The hepatic diabetes is closely correlated with the cirrhosis, and the manifestations of clinical symptoms of patients with cirrhosis and hepatic diabetes are multiple and complex, and we need to conduct the positive treatment of primary diseases, and strictly control the blood glucose level.