摘要
目的观察宫瘤消胶囊对子宫内膜异位症大鼠异位内膜体积及组织病理学的影响。方法选取造模成功的雌性大鼠52只随机分为模型组、桂枝茯苓胶囊组、宫瘤消胶囊小、中、大剂量组,灌胃28天后,取出异位内膜组织,分别观察大鼠异位内膜病灶的组织病理学变化及其用药前后异位病灶的体积变化。结果宫瘤消胶囊能够破坏大鼠异位内膜正常组织结构,其中以宫瘤消胶囊中、大剂量效佳。结论宫瘤消胶囊有抑制异位病灶生长的作用。
Objective： To observe the effect of Gongliuxiao capsule on the volume of ectopic endometrium in rats with endometriosis. Method： 52 successful models of female rats were randomly divided into model group,Guizhi Fuling capsule group,Gongliuxiao capsule low,middle and high dose group. After 28 days of gavage,ectopic endometriotic tissues were removed and the histopathological changes of ectopic endometrial lesions and the volume changes of ectopic lesions before and after treatment were observed. Result： Gongliuxiao Capsule,especially the middle and high dose,can destroy the normal ectopic endometrial tissue of rats. Conclusion： Gongliuxiao capsule can inhibit the growth of ectopic lesions.
作者
姜虹
贺丰杰
朱虹丽
肖新春
王蓓蓓
Jiang Hong;He Fengjie;Zhu Hongli;Xiao Xinchun;Wang Beibei(Postgraduate of 2014 in Shaanxi University of Chinese Medicine, Xianyang 712046, China;Gynecology Department of Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang 712000, China)
出处
《现代中医药》
CAS
2018年第2期87-89,92,共4页
Modern Chinese Medicine
基金
国家中医药管理局重点学科资助项目
