儿童重症腺病毒肺炎预后不良的临床分析

Clinical Analysis of Poor Prognosis in Children with Severe Adenovirus Pneumonia

目的探讨儿童重症腺病毒肺炎预后不良的临床影响因素,以期为临床治疗提供参考。方法回顾性分析2013年7月至2016年7月我院收治的126例重症腺病毒肺炎患儿临床资料,探讨儿童重症腺病毒肺炎预后不良的临床影响因素。结果 126例重症腺病毒肺炎患儿预后不良31例。多元回归分析结果显示患儿年龄1岁以下、多器官功能损害、合并2种及以上并发症以及急性呼吸窘迫综合征(ARDS)是儿童重症腺病毒肺炎预后不良的独立危险因素。结论对于重症腺病毒肺炎预后不良,年龄在1岁以下、多器官功能损害、合并2种及以上并发症、伴发ARDS均是独立危险影响因素,在临床治疗过程中应针对相关因素进行干预,减少预后不良情况发生。

Objective To explore the clinical factors influencing poor prognosis in children with severe adenovirus pneumonia, so as to provide reference for clinical treatment. Methods The clinical data of 126 children with severe adenovirus pneumonia in our hospital from July 2013 to July 2016 were retrospectively analyzed,and the clinical factors influencing poor prognosis in children with severe adenovirus pneumonia were investigated. Results There were 31 cases with poor prognosis in 126 children with severe adenovirus pneumonia. Multivariate regression analysis showed that children under one year old, multiple organ dysfunction, two or more complications and acute respiratory distress syndrome（ARDS） were independent risk factors for poor prognosis in children with severe adenovirus pneumonia. Conclusion For children with severe adenovirus pneumonia, age under one year old, multiple organ dysfunction, two or more complications, and accompanied ARDS are independent risk factors for poor prognosis. Therefore, in order to reduce the incidence of adverse events, intervention for relevant factors should be carried out in the course of clinical treatment.