氢呼气试验在胃肠疾病诊断中的临床价值

Clinical Study on the Application of Hydrogen Exhalation Test in the Diagnosis of Gastrointestinal Diseases

目的探究氢呼吸试验在临床上诊断胃肠疾病的效果。方法选取2015年8月到2017年2月期间来我院就诊的230例胃肠疾病(IBS)患者,其中包括腹泻型(IBS-D)患者80例,便秘型(IBS-C)患者80例,功能性消化不良(FD)患者70例,以及80例健康志愿者。给予受试患者和健康志愿者乳果糖氢呼气检测,比较各组受试者的一般资料,以及口盲传递时间(OCTT)和小肠细菌过度生长(SIBO)发生率。结果各组之间在性别、年龄、BMI以及Hp感染率无显著性差异(P>0.05)。在SIBO阳性率方面,IBS-D、IBS-C、FD组明显高于对照组,具有统计学差异(P<0.05)。在OCTT方面,IBS-D、IBS-C、FD组与对照组相比,具有显著性差异(P<0.05)。结论氢呼吸试验在临床上诊断胃肠疾病具有明显的效果。

Objective To explore the effect of hydrogen respiration test on the clinical diagnosis of gastrointestinal diseases.Methods A total of 230 gastrointestinal patients were enrolled in our hospital from August 2015 to February 2017,including 80 patients with diarrhea（IBS-D）and 80 patients with constipation（IBS-C）70 patients with dyspepsia（FD）,and 80 healthy volunteers.They were given the lactose hydrogen breath test,thencompare of the general data of each group of subjects,as well as the incidence of blindness transmission time（OCTT）and small intestinal bacterial overgrowth（SIBO）.Results There was no significant difference in sex,age,BMI and Hp infection rates among the groups（P〉0.05）of the general data.In the SIBO positive rate,IBS-D,IBS-C,FD group was significantly higher than the control group（P〈0.05）.In the OCTT,IBS-D,IBS-C,FD group compared with the control group,there was a significant difference（P〈0.05）.Conclusion The hydrogen respiration test has obvious effect in the clinical diagnosis of gastrointestinal diseases.