儿童视神经脊髓炎谱系疾病诊治进展

Progress in diagnosis and treatment of neuromyelitis optica spectrum disorders in children

目前人们对儿童视神经脊髓炎谱系疾病(NMOSD)的发病机制、临床表现、诊断、治疗、预后的认识仍处在了解及研究阶段。很多方面尚未达成共识,存有诸多争议,但作为预后不容乐观的中枢神经系统脱髓鞘病变,严重病例确实会遗留永久中枢神经系统不可逆的损害,因此,早期识别、诊断及治疗儿童NMOSD对于改善患儿的预后及长期的生活质量均有重要的临床和社会意义。

At present, the people are still in the understand- ing and research stage of the pathogenesis, clinical manifesta- tion, diagnosis, treatment and prognosis of children with Neuro- myelitis spectrum disorder （NMOSD）. In many aspects of the disease, there is still some controversy and no consensus. How- ever, the prognosis of NMOSD is poor, and severe cases can cause permanent irreversible damage to the central nervous system. Therefore, early identification, diagnosis and treatment of the disease have important clinical and social significance for children＇ s prognosis and long-term quality of life.