OSAHS与慢性耳鸣相关性的初步探讨

A preliminary study on the correlation between obstructive sleep apnea hypopnea syndrome and chronic tinnitus

目的:了解OSAHS患者慢性耳鸣伴发情况,并探讨其相关因素。方法:研究对象为通过PSG监测检查诊断为OSAHS的115例患者,通过病史调查了解伴发耳鸣的患者数量,计算所有患者的BMI。利用单因素与多因素Logistic分析计算性别、年龄、听力下降、BMI、最低血氧饱和度、REM期时长与主观性耳鸣发生的相关性,用χ~2检验比较各年龄组及男女间耳鸣伴发率的差异性。结果:(1)115例OSAHS患者中,主观性耳鸣患病率为38.26%(44/115)。(2)31~40岁、41~50岁、51~60岁、61~70岁、71~80岁患者耳鸣伴发率分别为9.09%、6.82%、11.36%、38.64%、29.55%,组间差异有统计学意义(χ~2=14.55,P<0.01);女性耳鸣伴发率为44.12%(15/34)、男性为35.80%(29/81),女性高于男性,但组间差异无统计学意义(χ~2=0.70,P>0.05)。(3)单因素及多因素Logistic回归分析结果均显示,性别、BMI、REM期时长及最低血氧饱和度与OSAHS患者耳鸣发生无相关性,而年龄与听力下降为耳鸣发生的独立相关因素(P<0.05)。结论:OSAHS患者超过1/3伴发慢性耳鸣,BMI、REM期时长及最低血氧饱和度与耳鸣发生无明确相关性,年龄与听力下降为OSAHS患者耳鸣发生的危险因素。

Objective：To investigate and analyze the chronic tinnitus＇ prevalence and its related factors in OSAHS patients.Method：We studied 115 patients who were diagnosed with OSAHS by polysomnography.All patients＇ BMI were calculated.The amount of patients accompanying tinnitus was calculated by investigating the history of tinnitus.Univariate and multivariate logistic analyzes were used to calculate the association between gender,age,hearing loss,BMI,and the lowest SPO_2 with tinnitus.The differences in tinnitus prevalence among different age groups and gender were compared using chi-square test.Result：（1）The prevalence of tinnitus in 115 OSAHS patients was 38.26%（44/115）.（2）Between the ages of 31-80 years,the prevalence of tinnitus in every10-year-old group was 9.09%,6.82%,11.36%,38.64%,and 29.55%,respectively.There was a significant difference between the age groups（χ~2=14.55,P0.01）.The prevalence of female was 44.12%（15/34）which was higher than the male 35.80%（29/81）,there was no significant difference（χ~2=0.70,P〉0.05）.（3）The results of univariate and multivariate logistic regression analysis showed that sex,BMI and lowest SPO_2 had no correlation with tinnitus in patients with OSAHS,while age and hearing loss were independent correlates of tinnitus（P〈0.05）.Conclusion：More than 1/3 of patients with OSAHS had chronic tinnitus,both age and hearing loss maybe the risk factors of tinnitus in patients with OSAHS,but neither BMI nor the lowest SPO_2 was clearly related to chronic tinnitus.