中药熏眼联合雷火灸治疗干眼症的临床效果

Clinical Observation on Chinese herbal medicine Fumigating Eyes Combined with Thunder-fire Moxibustion in the Treatment of Dry Eye Syndrome

目的:观察中药熏眼联合雷火灸治疗干眼症的临床疗效。方法:选取2015年3月至2016年8月广东省第二中医院眼科门诊干眼症患者120例(共240只眼),随机分为人工泪液+中药熏眼+雷火灸(A组),人工泪液对照组(B组),人工泪液+中药熏眼对照组(C组),人工泪液+雷火灸对照组(D组),每组各30例(60只眼)。A组予以自拟中药熏蒸双眼,1次/d;雷火灸熏双眼,1次/d;羟丙甲纤维素滴眼液点双眼,4次/d。B组予以羟丙甲纤维素滴眼液点双眼,4次/d。C组予以自拟中药熏蒸双眼,1次/d;羟丙甲纤维素滴眼液点双眼,D组予以雷火灸熏双眼,1次/d;羟丙甲纤维素滴眼液点双眼,4次/d。疗程均为10 d,观察4组患者治疗前后的临床症状评分、泪膜破裂时间(BUT)、泪液分泌实验(Schirmer test I)、角膜荧光素染色(FL),比较4组临床效果。结果:A组治疗有效率为96.7%,B组治疗有效率为60.0%,C组治疗有效率均为80.0%,D组治疗有效率均为83.3%,A组与B、C、D组间比较差异有统计学意义(P<0.05)。A组的临床症状评分、BUT、Schirmer test I评分、FL评分与B、C、D组间比较,差异均有统计学意义(P<0.05)结论:在人工泪液治疗干眼症的基础上结合中药熏眼、雷火灸能够获得较显著的治疗效果。

Objective： To observe the clinical curative effect of traditional Chinese medicine fumigating eyes combined with thunder-fire moxibustion on the treatment of dry eye syndrome. Methods： A total of 120 dry eye patients（ 240 eyes） from outpatient department of Guangdong Second Traditional Chinese Medicine Hospital during March 2015 and August 2016 were randomly divided into four groups： artificial tears ＋ Chinese herbal medicine fumigating eyes ＋ thunder fire moxibustion（ group A）,the artificial tears control group（ group B）,artificial tears ＋ Chinese herbal medicine fumigating eyes control group（ group C）,artificial tears ＋ thunder fire moxibustion group（ group D）,with 30 cases in each group（ 60 eyes）. Group A was treated with Chinese herbal medicine fumigating eyes once a day,thunder fire moxibustion fumigating eyes once a day,and Hypromellose Eye Drops dripping eyes four times a day. Group B received Hypromellose Eye Drops dripping eyes four times a day. Group C was treated with Chinese herbal medicine fumigating eyes once a day and Hypromellose Eye Drops dripping eyes four times a day; Group D received thunder fire moxibustion fumigating eyes once a day and Hypromellose Eye Drops dripping eyes four times a day. The course of treatment was 10 days. The clinical effect on each group,the four groups were observed before and after treatment about clinical symptom score,break-up time（ BUT）,Schirmer test（ Schirmer test I）,and corneal fluorescein staining（ FL） were compared.Results： The total effective rate of Group A was 96. 7%,60. 0% of group B,80. 0% of group C,and 83. 3% of group D. There was significant difference between group A and B,C,D（ P〈0. 05）. There were also significant differences in clinical symptom score,BUT,Schirmer test I score and FL score between group A and B,C,D（ P〈0. 05）. Conclusion： Artificial tears for the treatment of dry eye syndrome combined with Chinese herbal medicine fumigating eyes,thunder-fire moxibustion can obtain obvious therapeutic effect,which is worthy of clinical application and promotion.