摘要
骨质疏松症(Osteoporosis,OP)是一种以骨量低下、骨微结构破坏,导致脆性骨折的退行性骨病。阿尔茨海默病(Alzheimer's Disease,AD)主要表现为记忆力减退和认知功能障碍。表面上看OP和AD不论是在症状还是在体征方面都截然不同,但越来越多的研究表明两者存在一些共有的致病因素、发病机制和信号通路。
Osteoporosis（ OP） can be defined as a degenerative bone disease characterized by low bone mass and the microarchitectural deterioration,with a consequent increase in the fragility of bone and susceptibility to fracture. Alzheimer＇s disease（ AD）is a disease with memory loss and cognitive impairment. Despite their different signs and symptoms,these two diseases share many common risk factors,pathogenesis and signaling pathways.
作者
朱音
舒冰
王拥军
王晶
Zhu Yin;Shu Bing;Wang Yongjun;Wang Jing(Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China;Huadong Hospital Affiliated to Fudan University, Shanghai 200040, China;Institute of Spine, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China;Key Laboratory of Theory and Therapy of Muscles and Bones, Ministry of Education, Shanghai 200032, China)
出处
《世界中医药》
CAS
2018年第2期517-521,共5页
World Chinese Medicine
基金
国家科技部重点领域"创新团队"(2015RA4002)
国家教育部"创新团队发展计划"(IRT1270)
