摘要
α1抗胰蛋白酶（α1-antitrypsin，AAT）是一种丝氨酸蛋白酶抑制蛋白，其缺乏所致的AAT缺乏症（AAT deficiency，AATD）可引起肺部和肝脏疾病。目前治疗AATD相关的肺部疾病的常用方法是静脉注射人血AAT制剂，一些治疗AATD的新方法也在不断开发。此文就AATD的治疗研究做一综述。
Lack of serine protease inhibitor α1-antitrypsin （AAT） can lead to AAT deficiency （AATD）, which can cause lung and liver diseases. At present, the common treatment for AATD-related pulmonary diseases is intravenous administration of AAT derived from human plasma. Some new medical treatments for AATD are under development. This review summarizes therapeutic studies on AATD.
作者
任沁
周旭
Ren Qin;Zhou Xu.(No. 5 Research Laboratory, Shanghai Institute of Biological Products Co., Ltd., Shanghai 200051, China)
出处
《国际生物制品学杂志》
CAS
2018年第2期91-94,96,共5页
International Journal of Biologicals
