三维打印材料在骨组织工程中的研究进展

Research Progress of 3D Printing Materials in Bone Tissue Engineering

骨科手术的需求很大程度上促进了骨组织工程技术的进步。生产用于创伤修复手术的支架材料是一个骨组织工程研究中值得关注和正在进行的研究课题。在支架生产领域,3D打印在微观和宏观结构构建方面具有前所未有的精度,它可以被用来构建各种不同骨及软骨组织修复的生物工程材料支架。本文旨在寻找3DP的各种方法、所用的材料、功能和设计元素,以及改进3DP支架的生物力学性能与生物活性。

Orthopaedic surgery lends itself well to advances in technology. An area of interest and ongoing research is that of the production of scaffolds for use in trauma and elective surgery. 3D printing provides unprecedented accuracy in terms of micro- and macro-structure and geometry for scaffold production. It can also be utilised to construct scaffolds of a variety of different materials and more recently has allowed for the construction of bio-implants which recapitulate bone and cartilage tissue. This review seeks to look at the various methods of 3DP, the materials used, elements of functionality and design, as well as modifications to increase the biomechanics and bioactivity of 3DP scaffolds.