中暑患者血清心肌酶水平变化与患者病情判断及预后的关系

Variations of Myocardial Enzyme in Heatstroke Patients and Their Clinical Significance for Prognosis

目的观察中暑患者血清中心肌酶水平的变化,探讨血清心肌酶水平在中暑患者病情评估及预后判断中的临床价值。方法选取2014年3月-2017年9月期间渭南市中心医院急诊科收住的120例中暑患者,根据患者病情将其分为轻症中暑组(67例)和重症中暑组(53例),同时收集100例健康对照作为本研究的对照组人群,分别抽取5 ml静脉血,检测血清心肌酶的变化水平。此外,根据预后情况比较中暑患者血清心肌酶水平,并实时监测心肌标志物CK-MB在30 d的动态变化水平,并进行相关分析。结果中暑患者心肌酶水平较正常对照均有不同程度升高,且均与病情呈正相关关系;心肌标志物CK-MB动态变化水平表明心肌酶的水平随病情的改善呈恢复趋势,心肌酶水平高的患者预后相对较差。结论中暑患者血清心肌酶水平的检测有利于患者的病情评估和预后判断。

Objective To explore the clinical significance of changes of myocardial enzyme for clinical assessment of severity and the prognosis of heatstroke patients. Methods A total of 120 heatstroke patients treated at the Central Hospital of Weinan and another 100 normal controls were enrolled in this study. The 120 heatstroke patients were divided into two groups： light HS group and severe HS group based on their conditions. The levels of serum myocardial enzyme CK,CK-MB,AST and LDH were determined and their clinical significance for prognosis of heatstroke patients was evaluated. Results The level of myocardial enzyme was significantly higher in the light HS group than in the severe HS group,and it was positively correlated with the conditions and prognosis of heatstroke patients. Conclusion The determination of the level of myocardial enzyme in heatstroke patients is of great value in evaluating the severity and prognosis for heatstroke patients.