常见非降糖药物对血糖的影响

The effects of common non-hypoglycemic drugs on blood glucose

糖代谢通过神经、激素等的调控,正常情况下血糖的来源和去路保持动态平衡,维持在一定范围内。该平衡破坏时可导致血糖的波动如高血糖或低血糖,进而影响患者的生活质量,威胁人类健康。大多数患者通常需要多药物联合治疗,伴随联合使用药物之间相互作用,使得血糖的波动性风险增大。因此,对于血糖波动性的控制,药物的选择尤其是联合用药显得非常重要。本文将对非降糖治疗药对血糖代谢的影响作一文献综述。

Blood glucose metabolism through nerve and hormone regulation, the source and the metabolic of the blood glucose to keep the dynamic balance under normal circumstances, which maintain within a certain range. If the balance is destructed, which can lead to blood glucose ？uctuation, such as hyperglycemia or hypoglycemia, and then affects the patient＇s quality of life, also threatens human health. Most of the patients usually require multidrugs combination therapy, the combination of drug interactions, which increases the risk of blood glucose fluctuation. Therefore, in order to control the blood glucose ？uctuation, the choice of drugs, especially the combination of drugs, is very important. This reviews summarizes the effects of common non-hypoglycemic drugs on blood glucose.