以首发精神症状的神经梅毒患者临床特征分析

Clinical analysis of onset of psychiatric symptoms in neurosyphilis patients

目的总结以精神症状为首发神经梅毒患者的临床特点,为临床早期确诊神经梅毒提供线索。方法回顾性分析25例神经梅毒患者的精神病性症状。结果 25例患者中,误诊16例,主要误诊为双相情感障碍、精神分裂症、分裂样精神病、阿尔茨海默病、精神发育迟滞;精神病性症状共有25例,情感症状20例,认知功能改变22例,人格改变16例。结论首发精神症状的神经梅毒精神病性症状丰富,误诊率高,及时治疗能够改善精神症状。

Objective To summarize the clinical feature of onset of psychotic symptoms in neurosyphilis patients, and assist the diagnose of neurosyphilis. Methods Retrospetcive analysis the psychotic symptoms in 25 neurosyphilis patients. Results There are 16 misdiagnosis, which were diagnosed as bipolar disorder, schizophrenia, schizophrenic psychosis, AD, mental retardation.25 onset symptoms are psychotic symptoms, 20 are affective symptoms, cognition decline are 22, personality abnormal are 16. Conclusion The psychiatric symptoms are varies in neurosyphilis patients and often misdiagnosed, and can be improved after treatment.