草酸艾司西酞普兰对腹腔镜子宫肌瘤剥除术后患者焦虑抑郁及性生活质量的影响

Effects of escitalopram on anxiety,depression and sexual life quality in patients after laparoscopic myomectomy

目的探讨草酸艾司西酞普兰对腹腔镜子宫肌瘤剥除术(LM)后患者焦虑抑郁状态及性生活的影响。方法收集2015年2月~2017年2月我院收治的LM术后伴焦虑抑郁状态患者74例,随机分为观察组与对照组,各37例。对照组予以常规心理学干预,观察组在对照组的基础上加用草酸艾司西酞普兰口服。12周后比较两组患者治疗前后汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)、女性性功能评价表(BISF-W)评分。结果两组治疗后HAMA、HAMD评分均显著降低,且观察组显著低于对照组(P<0.05);两组治疗后BISF-W各项评分均显著提高,且观察组显著高于对照组(P<0.05)。结论草酸艾司西酞普兰可减轻LM患者术后焦虑抑郁状态,改善性生活质量。

Objective To investigate the effect of escitalopram on anxiety, depression and sexual life quality of patients after laparoscopie myomectomy （LM） . Methods From February 2015 to February 2017, total of 74 patients with anxiety and depression after LM in our hospital were enrolled and randomly divided into observation group and control group, each group with 37 patients. The control group received conventional psychological intervention, while the observation group received escitalopram on the basis of the control group. The Hamilton Anxiety Scale （ HAMA ）, Ham- ilton Depression Scale （ HAMD ） and Brief Index of Sexual Functioning for Women （BISF-W） were used to evaluate all the subjects before and after 12 weeks＇ treatment. Results The scores of HAMA and HAMD in the two groups were significantly lower after treatment, and the scores in observation group were significantly lower than those in the control group （P 〈 0.05 ） . The scores of BISF-W in the two groups were significantly higher after treatment, and the scores in observation group were significantly higher than those in the control group （P 〈 0.05 ） . Conclusion Escitalopram can alleviate the level of anxiety and depression and improve the sexual life quality in patients after LM.