经鼻持续气道正压通气治疗新生儿重症肺炎呼吸衰竭的疗效分析

Efficacy of Nasal Continuous Positive Airway Pressure Ventilation in Treating Neonatal Severe Pneumonia Respiratory Failure

目的分析研讨经鼻持续气道正压通气治疗新生儿重症肺炎呼吸衰竭的临床疗效。方法用数字法从我院2015年2月至2017年3月收治的新生儿重症肺炎呼吸衰竭患儿中抽取25例进行分析,患儿均接受经鼻持续气道正压通气治疗,比较治疗前后患儿炎性因子、体液免疫指标等。结果对比两组患儿炎性因子、体液免疫指标,治疗后IL-8、IL-6、IgM、IgM、IgA均低于治疗前,IL-2高于治疗前,且P<0.05。结论建议临床治疗新生儿重症肺炎呼吸衰竭给予经鼻持续气道正压通气方式,可改善体液免疫指标和炎性因子等,值得应用。

Objective To analyze the clinical efficacy of nasal continuous positive airway pressure in the treatment of respiratory failure in neonates with severe pneumonia.Methods 25 children with severe neonatal respiratory failure who were admitted to our hospital from February 2015 to March 2017 were enrolled in this study.All children underwent nasal continuous positive airway pressure ventilation.Inflammatory factors in children before and after treatment,humoral immune indicators.Results IL-8,IL-6,IgM,IgM and IgA were both lower than those before treatment in the two groups,and IL-2 was higher than before treatment and P〈0.05.Conclusion It is suggested that clinical treatment of neonatal severe pneumonia respiratory failure to give nasal continuous positive airway pressure ventilation,can improve the humoral immune indicators and inflammatory factors,it is worth to apply.