小儿热速清颗粒治疗儿童甲型流感风热犯卫证临床观察

Clinical Observation of Xiao'er Resuqing Granules for Influenza A with Syndrome of Wind-heat Invading the Wei-exterior in Children

目的:观察小儿热速清颗粒治疗儿童甲型流感风热犯卫证的临床疗效。方法:将140例儿童甲型流感风热犯卫证患者随机分为对照组和观察组,每组70例。对照组给予奥司他韦颗粒治疗,同时给予解热镇痛、抗过敏、止咳等药物对症处理,观察组在对照组治疗基础上加用小儿热速清颗粒。比较2组临床疗效,记录患儿治疗不同时间段腋温、退热时间及风热犯卫证评分。结果:观察组总有效率96.97%,高于对照组的84.62%,差异有统计学意义(P<0.05)。治疗后2组腋温均逐渐下降,观察组腋温在治疗24 h、48 h后均低于对照组(P<0.05)。治疗72 h,2组腋温比较,差异无统计学意义(P>0.05)。观察组退热时间短于对照组,差异有统计学意义(P<0.05)。治疗后,2组发热、咳嗽、鼻塞流涕及汗出评分均较治疗前降低(P<0.01);观察组发热、咳嗽、鼻塞流涕及汗出评分均低于对照组(P<0.01)。结论:在西药治疗基础上加用小儿热速清颗粒治疗风热犯卫型甲型流感,能有效减轻患儿的临床症状,快速退热,效果优于单纯西药治疗。

Objective：To observe the clinical effect of Xiao＇er Resuqing granules for influenza A with syndrome of wind-heat invading the wei-exterior in children.Methods：Divided 140 cases of children with influenza A with syndrome of wind-heat invading the wei-exterior into the control group and the observation group randomly,70 cases in each group.The control group was treated with oseltamivir granules along with symptomatic treatment including antipyretic analgesic,antiallergic,antitussive and other medicine.The observation group was additionally given Xiao＇er Resuqing granules based on the treatment of the control group.Compared the clinical effect of the two groups and recorded the axillary temperature and antipyretic time at different time periods as well as symptom scores of syndrome of wind-heat invading the wei-exterior after treatment.Results：The total effective rate was 96.97% in the observation group,higher than that in the control group which was 84.62%,the difference being significant（P 0.05）.After treatment,the axillary temperature in both groups was decreased when compared with that before treatment and the axillary temperature after 24 h and 48 h of treatment in the observation group was lower than that in the control group（P 0.05）.After 72 h of treatment,there was no significant difference being found in the comparison of axillary temperature（P 0.05）.The antipyretic time in the observation group was shorter than that in the control group,the difference being significant（P 0.05）.After treatment,scores of fever,cough,stuffy or runny nose and sweating were all decreased when compared with those before treatment（P 0.01）.Scores of the above symptoms in the observation group were lower than those in the control group（P 0.01）.Conclusion：Based on the treatment of western medicine,the additional application of Xiao＇er Resuqing granules for influenza A with syndrome of wind-heat invading the wei-exterior in children can effectively alleviate the clinical symptoms of children and reduce the fever rapidly,whose effect is superior to the simple western medicine treatment.