骨导振动刺激诱发的眼肌前庭诱发肌源性电位在正常国人人群中的波形特征

Characteristics of the bone conducted ocular evoked myogenic potential in the normal people

目的介绍骨导振动刺激诱发的眼肌前庭诱发肌源性电位(ocular vestibular-evoked myogenic potential,o VEMP)的引出方法;观察健康正常国人人群o VEMP反应,并进行参数分析和正常值计算。方法选择21名健康成人作为研究对象,其中男9名(18耳),女12名(24耳);年龄20~43岁,平均29岁。以振动强度为127 d B SPL的刺激强度诱发辨认正常波形,每隔10 d B SPL逐渐减少刺激强度记录到出现反应的最小刺激强度,并计算潜伏期、振幅、波间期、阈值正常值。结果 21名双耳均引出典型的o VEMP波形,引出率为100%。骨导振动o VEMP引出的振动刺激阈值为(103.9±10.2)d BSPL;N1潜伏期为(9.8±1.3)ms,P1潜伏期为(13.2±1.7)ms,波间期为(3.4±1.2)ms,振幅为(13.2±7.4)μv。双耳间骨导o VEMP N1潜伏期、P1潜伏期、振幅、波间期及阈值波动均较小。结论骨导o VEMP是一项稳定、可靠、新兴的前庭功能检测方法。

Objective To indentify the characteristics of the bone conducted ocular vestibular-evoked myogenic potential（oVEMP）in the normal people in China.Methods Twenty one normal subjects were recruited for conventional examinations of bone conducted oVEMP.The subjects were 20-43 years old（average age was 29 years old）,nine males and 13 females.The normal waveform was induced by the stimulation intensity of 127dB SPL,and the intensity of stimulus was recorded at every 10dB SPL.The minimum stimulus intensity was recorded,and the latency,amplitude,interphase and threshold value were calculated.Results All subiects were elicited with normal oVEMP N1-P1 waves in both ears.The response rate in these subjects Was 100%.The threshold of oVEMP examination was（103.9±10.2）dBSPL,latency N1（9.8±1.3）ms,latency P1（13.2±1.7）ms,interval N1-P1（3.4±1.2）ms,amplitude（13.2±7.4）μv.Conclusions Bone conducted oVEMP is a stable,reliable and new method for the detec-tion of vestibular function.