213例甲状腺功能亢进症患者临床主症特点分析

Clinical characteristics of main symptoms in 213 patients with hyperthyroidism

目的通过归纳甲状腺功能亢进症(甲亢)患者临床主症类别及临床疗效变化,对不同主症患者的临床变化特点进行探讨。方法收集2010年1月-2016年12月期间收治的甲亢患者病历信息,记录患者诊断年龄、性别、临床主诉症状、用药类别及甲状腺功能水平、临床主诉症状消失时间等指标进行统计分析。结果以消瘦为主症的患者治疗前FT3、FT4水平明显高于乏力、心悸、怕热多汗患者(P<0.05);与其他主症患者相比,心悸的患者症状缓解所需时间最短(P<0.05),消瘦症状缓解所需时间最长(P<0.01);怕热多汗症状与TPOAb间存在一定的相关性(P<0.05)。结论临床主症类别与甲状腺抗体水平、甲状腺功能变化趋势、症状缓解时间等相关,不同主症间互相存在显著差异。

Objective Through concluding main symptoms and clinical curative effect changes of the hyperthyroidism patients,to discuss the main symptoms characteristics of patients.Methods All hyperthyroidism patients from January,2010 to December,2016 were retrospectively analyzed,included diagnosis of age,gender,main clinical symptoms and signs,medication category,thyroid function,symptom disappearance time index to analyze the clinical features and curative effects.Results Weight reduction as the main symptoms of hyperthyroidism patients＇ FT3,FT4 levels were significantly higher than those patients with fatigue,tachycardia,and hidrosis before treatment（P〈0.05）.Compared with other main symptoms,the shortest time needed for patients was tachycardia symptoms（P〈0.05）,weight reduction was the longest one（P〈0.01）;Hidrosis and TPOAb were in crosscorrelation（P〈0.05）.Conclusion Different clinical main symptom of hyperthyroidism patients is mutually related with the thyroid antibody levels,thyroid function changes,and symptoms remission time.