摘要
BACKGROUND: Venous thromboembolism(VTE), including both deep vein thrombosis(DVT) and pulmonary embolism(PE), is a common, lethal disorder that affects hospitalized and nonhospitalized patients. This study aimed to review the progress in the research into VTE.DATA SOURCES: We reviewed the studies about VTE and verified different genetic polymoriphisms of VTE.RESULTS: The pathogenesis of VTE involves hereditary and acquired factors. Many studies indicated that the disorder of coagulation and fibirnolytic system is of utmost importance to this disease. Genetic polymoriphism-related VTE demonstrated significant differences among geographies and ethnicities.CONCLUSION: VTE has many risk factors, but genetic factors play an important role.
BACKGROUND： Venous thromboembolism （VTE）, including both deep vein thrombosis （DVT） and pulmonary embolism （PE）, is a common, lethal disorder that affects hospitalized and non- hospitalized patients. This study aimed to review the progress in the research into VTE. DATA SOURCES： We reviewed the studies about VTE and verified different genetic polymoriphisms of VTE. RESULTS： The pathogenesis of VTE involves hereditary and acquired factors. Many studies indicated that the disorder of coagulation and fibirnolytic system is of utmost importance to this disease. Genetic polymoriphism-related VTE demonstrated significant differences among geographies and ethnicities. CONCLUSION： VTE has many risk factors, but genetic factors play an important role.
