蚯蚓体内外分泌液的抗菌活性研究

Study on the Antibacterial Activity of Internal and External Secretory Fluid of Earthworm

[目的]探究蚯蚓体内外分泌液的抗菌活性。[方法]分别将蚯蚓体内外分泌液作用于不同的临床致病菌株,筛选对体内外分泌液的敏感菌种,并在此基础上分析温度、pH、蚯蚓体内外分泌液浓度等因素对蚯蚓分泌液抗菌效果的影响。[结果]蚯蚓体内外分泌液均对金黄色葡萄球菌有良好的抗菌效果;诱发最佳抗菌效果的环境条件为:内分泌液原液、30℃、pH 7~8;外分泌液原液、60℃、pH 7~8。[结论]研究结果为更好地开发与利用蚯蚓资源提供了理论基础和实践依据。

[Objective] To study the antibacterial activity of the internal and external secretory fluid of earthworm. [Method] The internal and external secretory fluid of earthworms were conducted on different clinical pathogens to screen out sensitive strains of internal and external secretory fluids. On this basis,the influences of temperature,pH,the concentration of internal and external secretory fluid of earthworms and other environmental factors on the antibacterial effect of secretory fluid of earthworm were analyzed.[Result] The internal and external secretory fluids of earthworm had good antibacterial effects on Staphylococcus aureus. The environmental conditions to induce the optimum antibacterial effect were as follows： the original liquid of the internal secretory fluid,30 ℃,pH 7-8; the original liquid of external secretory fluid,60 ℃,and pH 7-8.[Conclusion] The research results provided theoretical basis and practical basis for better exploitation and utilization of earthworm resources.