胃肠道间质瘤75例临床疗效分析

Clinical Analysis of 75 Cases of Gastrointestinal Stromal Tumor

目的对胃肠道间质瘤患者采取不同治疗方法的效果进行分析探讨。方法从2011年11月—2012年11月在我院进行治疗的胃肠道间质瘤患者中,选取75例予以研究,并将之分为三组,Ⅰ组采用完整切除手术,Ⅱ组采用靶向药物治疗,Ⅲ组联合使用完整切除手术和靶向药物治疗,对比三组治疗方式患者的生存情况。结果Ⅲ组患者的生存情况优于Ⅰ组和Ⅱ组,差异具有统计学意义(P<0.05);而Ⅰ组和Ⅱ组患者的预后生存率差异不具有统计学意义(P>0.05)。结论对于胃肠道间质瘤患者,联合使用手术治疗和靶向药物治疗,具有良好的治疗效果。

Objective To analyze the efect of diferent treatment methods for patients with gastrointestinal stromal tumors. Methods Seventy-fve patients with gastrointestinal stromal tumors treated in our hospital from November 2011 to November 2012 were selected and divided into three groups. Group I was treated with complete resection and targeted drug therapy was used in group II, group III combined with complete resection and targeted drug therapy, compared the survival of patients in the three groups of treatment. Results The survival of patients in group III was signifcantly better than those in group I and II （P 〈 0.05）. The survival rate of patients in group I and group II was not significantly different （P 〉 0.05）. Conclusion For patients with gastrointestinal stromal tumors, combined use of surgical treatment and targeted drug therapy has a good therapeutic efect.