不同胰岛素给药方法治疗糖尿病的临床效果对比

Clinical effect comparison of different insulin delivery methods on diabetes mellitus

目的探究不同胰岛素给药方法治疗糖尿病的临床效果。方法选取我院2016年6月~2017年8月收治的91例糖尿病患者作为研究对象,根据给药方式分为对照组(42例)和治疗组(49例),对照组患者采取皮下注射胰岛素治疗,治疗组患者采取胰岛素泵输注胰岛素治疗,比较两组患者的临床治疗效果。结果治疗组患者总有效率为95.92%,高于对照组(83.33%),差异有统计学意义(P<0.05);治疗组患者治疗后空腹血糖水平为(6.23±0.85)mmol/L,低于对照组(7.15±1.23)mmol/L,治疗组患者空腹血糖达标时间短于对照组,平均胰岛素用量低于对照组,差异均有统计学意义(P<0.05);治疗组患者低血糖发生率为2.04%,低于对照组(14.29%),差异有统计学意义(P<0.05)。结论糖尿病患者采取胰岛素泵治疗方法,可以减少胰岛素用量,疗效高,对患者空腹血糖改善起到显著的作用,利于患者血糖控制,在临床治疗中具有重要的应用价值。

Objective To explore the clinical effect of different insulin delivery methods on diabetes mellitus（DM）.Methods 91 cases DM patients from June 2016 to August 2017 were selected as research objects in our hospital.They were divided into control group（n=42） and treatment group（n=49） according to the mode of administration.In the control group,subcutaneous insulin therapy was used,while in the treatment group,insulin pump infusion therapy was adopted.The clinical efficacy of the two groups was compared.Results The total effectiveness rate of the treatment group was95.92%,significantly higher than that in the control group accounting for 83.33%,with a significant difference（P〈0.05）.The fasting blood glucose level in the treatment group after therapy was（6.23±0.85） mmol/L,lower than that in the control group（7.15±1.23） mmol/L.The time of fasting blood glucose meeting the standard in the treatment group was shorter,and the average insulin dose was lowerer compared with those in the control group,with statistical differences（P 〈0.05）.The incidence of hypoglycemia was 2.04%,lower than that in the control group accounting for 14.29%,with a statistical difference（P〈0.05）.Conclusion Insulin treatment in DM patients,insulin pump therapy can reduce the insulin dose in high effect,greatly improve the fasting blood glucose,and benefit patient′s glycemic control,and play an important application value in clinical treatment.