降钙素原、超敏C反应蛋白、白细胞计数在小儿呼吸道感染诊断中的价值

Value of PCT,hs-CRP and WBC in the diagnosis of respiratory tract infection in children

目的分析降钙素原(PCT)、超敏C反应蛋白(hs-CRP)、白细胞计数(WBC)在小儿呼吸道感染诊断中的价值。方法 2015年1月至2016年6月湖南省儿童医院儿科收治呼吸道感染患儿116例,根据实验室检查结果分为细菌组52例和病毒组64例。同期选取健康儿童58例为对照组,对比3组儿童PCT、hs-CRP、WBC水平。结果细菌组患儿PCT、hs-CRP、WBC阳性率均显著高于病毒组、对照组,差异有统计学意义(P<0.05),且三者联合检测阳性率显著高于病毒组、对照组,差异有统计学意义(P<0.017);病毒组患儿PCT、hs-CRP、WBC阳性率与对照组比较差异无统计学意义(P>0.017)。细菌组患儿PCT、hs-CRP、WBC水平显著高于病毒组、对照组,差异有统计学意义(P<0.05);病毒组患儿PCT、hsCRP、WBC水平与对照组对比差异无统计学意义(P>0.05)。结论 PCT、hs-CRP、WBC三者联合检测能够显著提高小儿呼吸道感染的阳性检出率,具有重要的临床意义。

Objective To study the significance of joint detection of PCT,hs-CRP and WBC in the diagnosis of children with respiratory tract infection.Methods Totally 116 cases of respiratory tract infection were randomly selected from January 2015 to June 2016 in Hunan Children＇s Hospital,and according to the different diagnostic results,they were divided into bacterial infection group（n=52）and virus group（n=64）,and select 58 cases of healthy children at the same period as control group.Compared PCT,hs-CRP and WBC among three groups of children.Results The positive rate of PCT,hs-CRP and CRP in bacteria infection group was significantly higher than that of virus infection group and control group（P〈0.05）,and there was no significant difference between virus infection group and control group（P〈0.05）.The PCT,hsCRP and CRP concentration of bacteria infection group was significantly higher than the other two groups（P〈0.05）,and there was no difference between virus infection group and control group（P〉0.05）.Conclusion The combined detection of PCT,hs-CRP and WBC can significantly improve the positive rate of diagnosis of children with respiratory tract infection,and has important clinical significance.