EAT-10在高级别脑胶质瘤患者中应用的意义

The significance of eating assessment tool-10 in high-grade gliomas

目的探讨对存在吞咽障碍的高级别脑胶质瘤患者留置鼻胃管的合适时机。方法回顾性分析32例留置鼻胃管的高级别脑胶质瘤患者,将选择立即置入鼻胃管者设为观察组,共17例,将选择延期置入鼻胃管者设为对照组,共15例。采用进食评估问卷调查工具-10进行评估,比较两组患者得分情况;比较两组患者的肺炎发生情况和生存时间;观察两组患者出现吞咽障碍症状后1个月和2个月的体重、体质指数、白蛋白、KPS评分和日常生活能力评分表等指标变化情况。结果进食评估问卷调查工具-10总分24分时,两组间肺炎发生情况比较差异有统计学意义(χ~2=4.802,P=0.028),观察组2例患者发生肺炎,发生率为11.76%,对照组7例患者发生肺炎,发生率为46.67%;吞咽症状出现后2个月,对照组患者KPS评分明显低于观察组,差异有统计学意义(t=-1.07,P=0.01)。结论应用进食评估问卷调查工具-10对高级别脑胶质瘤患者进行吞咽障碍症状评估时,当进食评估问卷调查工具-10总分达到24分时应该给予患者立即留置鼻胃管,如果选择延期留置鼻胃管,会增加患者发生肺炎的风险,影响患者的健康状况。

Objective To investigate the effect of different nasogastric tube retention time on quality of life and prognosis of glioma patients with deglutition disorders. Methods A retrospective analysis was performed on 32 glioma patients with nasogastric intestine. 17 patients were immediately placed into the nasogastric tube （immediate group）, and the other 15 patients were delayed into the nasogastric tube （delayed group）. The body weight, body mass index （BMI）, albumin, KPS score and daily living ability score table （ADL table） were measured at 1 month and 2 months after symptoms of deglutition disorder appear. We compared the survival time and the total EAT-10 score of the two groups. Results When the total score of EAT-10 was 24, the incidence of pneumonia between the two groups was statistically signifcant difference （χ2=4.802, P=0.028）. Pneumonia was observed in 2 patients in the observation group, with an incidence rate of 11.76%, and pneumonia was found in 7 patients in the control group with a rate of 46.67%. Two months after the onset of swallowing symptoms, the KPS scores of the control group were signifcantly lower than those of the observation group （t=-1.07, P=0.01）. Conclusions Patients with high-grade gliomas undergoing assessment of symptoms of deglutition disorder using the eating assessment tool -10 （EAT-10） should be given immediate nocturnal enuresis when the EAT-10 score reaches 24 points Stomach tube. If you choose to postpone the nasogastric tube, it will increase the risk of pneumonia patients, and thus affect the patient＇s health status.