摘要无先兆型偏头痛（migraine without aura,MO）是一种常见的神经血管紊乱疾病,属于偏头痛最常见的一种亚型,占其70%。在最新版国际头痛疾病分类标准（ICHD-Ⅲ）^（[1]）中,除了头痛发作外,其主要特点为单侧性、搏动性及影响日常活动,伴随畏光、畏声、恶心、呕吐等。目前认为MO为多基因遗传病,主要与遗传、物理和化学因素及激素的变化有关^（[2]）。
2Hargreaves RJ, Shepheard SL. Pathophysiology of mig- minenew insights. Can J Neurol Sci, 1999, 26:S 12 - 19.
3Headache classification committee of the international headache society (IHS). The international classification of headache disorders, 3rd edition (beta version). Ceph- alalgia, 2013, 33:629 - 808.
4Russell MB, Iselius L, Olesen J.Migraine without aura and migraine with aura are inherited disorders. Cephalalgia, 1996, 16:305 - 309.
5Breslau N, Schultz LR, Stewart WI, et al. Headache and major depression. Neurology, 2000, 54:308 - 313.
