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艾司奥美拉唑联合奥曲肽治疗肝硬化上消化道出血效果分析 被引量:3

Efficacy of Esomeprazole Combined with Octreotide in the Treatment of Liver Cirrhosis with Upper Gastrointestinal Bleeding
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摘要 目的:探讨艾司奥美拉唑联合奥曲肽治疗肝硬化上消化道出血的临床疗效。方法:抽取至某院就诊的肝硬化上消化道出血患者120例,收治时间为2014年5月17日~2017年5月17日,随机分为常规组和观察组,常规组单纯采取艾司奥美拉唑治疗,观察组艾司奥美拉唑+奥曲肽治疗,对比两组的临床疗效。结果:观察组的止血时间、输血量、住院时间相比常规组均明显较优,P<0.05;观察组与常规组的治疗总有效率分别为96.00%与80.00%,P<0.05。结论:对肝硬化上消化道出血患者而言,采取艾司奥美拉唑+奥曲肽进行治疗,可明显改善患者的临床症状,值得采纳。 Objective:To explore the clinical effect of esomeprazole combined with octrexine in the treatment of upper gastrointestinal hemorrhage in liver cirrhosis.Methods:120 cases of patients with liver cirrhosis upper gastrointestinal hemorrhage treated in a hospitalf from May 17 th,2014 to May 17 th,2017 were selected and randomly divided into routine group and observation group.One group was treated with esomeprazole alone and the other group was treated with esomeprazole and octreotide.The clinical efficacy of the two groups was compared.Results:The hemostasis time,blood transfusion volume and hospitalization time of the observation group were significantly better than those of the routine group(P〈0.05).The total effective rate of the observation group and the routine group was 96.00% and 80.005% respectively(P〈0.05).Conclusion:For patients with upper gastrointestinal bleeding due to liver cirrhosis,the author recommends the treatment of esomeprazole with octreotide,which can obviously improve the clinical symptoms of patients,and is worthy of adoption.
作者 张美平 邬宇美 李秀芬 Zhang Meiping;et al(Department of Internal Medicine, Shenzhen No.3 People's Hospital, Shenzhen 518000)
出处 《数理医药学杂志》 2018年第5期755-756,共2页 Journal of Mathematical Medicine
关键词 肝硬化 上消化道出血 奥曲肽 艾司奥美拉唑 cirrhosis upper gastrointestinal bleeding octreotide esomeprazole
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  • 1李忍萍.肝硬化门脉高压患者上消化道出血原因分析[J].山东医药,2005,45(1):54-55. 被引量:7
  • 2吴植彬.奥曲肽和奥美拉唑联合治疗肝硬化并上消化道出血36例分析[J].中原医刊,2005,32(21):8-9. 被引量:4
  • 3王余俊,卢晓霞,陈安平.奥曲肽和奥美拉唑治疗肝硬化并上消化道出血疗效分析[J].贵州医药,2006,30(11):1038-1039. 被引量:1
  • 4徐晖,庄丽维,刘娜,刘颖,梁桃.奥曲肽、生长抑素治疗肝硬化上消化道出血疗效观察[J].中国临床医学,2006,13(6):934-935. 被引量:49
  • 5柯美云.功能性胃肠病并非单纯功能病[J].中国实用内科杂志,2009,26(4):261~262.
  • 6Jadad AR,Moore RA,Carroll D,et al. Assessing the quality of reports of randomized e, linieal trials:Is blinding necessary[J]. Control Clin Tri- als, 1996, 17(1 ) : 1.
  • 7Cerini F, Gonzalez JM, Torres F, et al. Impact of anticoagulation on upper-gastrointestinal bleeding in cirrhosis. A retrospective multicenter study [ J ]. Hepatology ,2015, 62 ( 2 ) :575-583.
  • 8Lyles T, Elliott A, Rockey DC. A risk scoring system to predict in- hospital mortality in patients with cirrhosis presenting with upper gastrointestinal bleeding. [J]. J Clin Gastroenterol,2014, 48(8):712-720.
  • 9Lecleire S, Di FF, Merle V, et al. Acute upper gastrointestinal bleeding in patients with liver cirrhosis and in noncirrhotic patients: epidemiology and predictive factors of mortality in a prospective multieenter population-based study. [ J]. J Clin Gastroenterol, 2005,39 (39) :321-327.
  • 10Seo YS, Kim YH, Sang HA, et al. Clinical Features and Treatment Outcomes of Upper Gastrointestinal Bleeding in Patients with Cirrhosis[ J]. J Korean Med Sci ,2008,23 (4) :635-643.

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