绝经后女性卵泡刺激素与代谢综合征的关系

Relationship between FSH and metabolic syndrome in postmenopausal women

代谢综合征是一个多症候群的综合征,绝经后女性发病率增加,男女性有不同的发病规律。绝经后女性高卵泡刺激素似乎是代谢综合征的保护因素,但是相关临床和机制研究不足,且对代谢综合征各病理状态作用存在矛盾。高卵泡刺激素不利于血脂代谢,在激素补充治疗过程中血脂改善程度和卵泡刺激素下降幅度有关。本文就绝经后女性卵泡刺激素水平和代谢综合征的关系作一综述。

Metabolic syndrome is a complex of multiple syndromes.After menopause,the incidence of metabolic syndrome increases,men and women have different etiological pattern.High FSH seems to be aprotective factor of metabolic syndrome in postmenopausal women.However,the relevant clinical and mechanism studies are inadequate.FSH has a paradoxical effect on the components of metabolic syndrome.High FSH is harmful to the metabolism of blood lipids.In the process of hormone replacement therapy,the degree of blood lipid improvement is related to the decrease of FSH.This paper reviews the relationship between FSH and metabolic syndrome in the postmenopausal women.