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初诊类风湿关节炎患者外周血维生素D水平及其临床意义 被引量:7

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摘要 类风湿关节炎(rheumatoid arthritis,RA)是以侵蚀性、对称性多关节炎为主要临床表现的慢性、全身性自身免疫病。确切发病机制不明。基本病理改变为滑膜炎、血管翳形成,并逐渐出现关节软骨和骨破坏,最终可能导致关节畸形和功能丧失。最近的研究发现,维生素D可能作用于免疫细胞,发挥抗炎和免疫调节的作用,维生素D缺乏可以导致许多慢性,免疫性疾病。
出处 《中国药物与临床》 CAS 2018年第3期428-430,共3页 Chinese Remedies & Clinics
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