神经电生理监测结合神经导航技术切除脑干胶质瘤

Application of combination of intraoperative neuroelectrophysiological monitoring and neuronavigation multi-modal fusion technology in the glioma resection

目的分析术中神经电生理监测结合神经导航多模态融合技术在切除脑干胶质瘤中的应用价值。方法将120例脑干胶质瘤患者分为观察组及对照组,对照组行传统手术治疗,观察组行术中神经电生理监测结合神经导航多模态融合技术治疗;比较两组手术基本情况、临床疗效、KPS评分、并发症发生情况及生存率。结果观察组疗效明显高于对照组(76.66%vs.53.33%,χ~2=11.962,P=0.001);观察组KPS评分改善情况(27.91±1.98)优于对照组(12.11±2.13),且差异存统计学意义(t=32.669,P<0.001)。结论脑干胶质瘤患者采用术中神经电生理监测结合神经导航多模态融合技术切除后,可有助于提高临床疗效,改善生活质量。

Objective To analyze the application of intraoperative neurophysiological monitoring combined with neuronavigation multi-modal fusion technology in the brainstem glioma resection. Methods One hundred twenty patients with brainstem glioma were divided into observation group and control group. The control group was treated by traditional operation, while the observation group was treated by intraoperative nerve electrophysiological monitoring combined with neuronavigation multimodal fusion technology. The general condition, clinical efficacy, KPS score,complications and survival rate of the two groups were compared. Results The effect was significantly better in the observation group（76.66%）than in control group（53.33%）（ χ^2=11.962, P=0.001）. KPS scores were significantly higher in the observation group（27.91 ±1.98） than in the control group（12.11 ±2.13）（t =32.669, P〈0.001）. Conclusions Intraoperative nerve electrophysiological monitoring plus neuronavigation multimodality fusion technology can improve clinical efficacy and quality of life in patients with brainstem glioma.