静脉溶栓联合血管内介入治疗中重症急性脑梗死患者预后的影响因素分析

Analysis on the Influencing Factors of the Prognosis of Intravenous Thrombolysis Combined with Endovascular Intervention for the Treatment of Moderate or Severe Acute Cerebral Infarction

目的探讨静脉溶栓联合血管内介入治疗中重症急性脑梗死(ACI)患者预后的影响因素。方法收集144例行静脉溶栓联合血管内介入治疗的ACI患者的临床资料,根据患者的m Rs评分分为预后良好组和预后不良组,分析影响预后的因素。结果单因素分析显示,年龄、治疗后即刻NIHSS评分、房颤史、BMI、高血压病、高脂血症等为导致预后不良的因素(P<0.05);Logistic回归分析显示,年龄≥75岁、术后即刻NIHSS评分>10分、房颤史、高血压病为导致预后不良的独立危险因素(P<0.05)。结论高龄、治疗后即刻NIHSS评分>10分、房颤史、高血压病为导致静脉溶栓联合血管内介入治疗预后不良的独立危险因素。

Objective To explore the influencing factors of the prognosis of intravenous thrombolysis combined with endovascular intervention for the treatment of moderate or severe acute cerebral infarction （ACI）. Methods The clinical data of 144 cases of ACI patients with intravenous thrombolysis combined with endovascular intervention were collected. According to the mrs score, all patients were divided into good-prognosis group and poor-prognosis group. The factors influencing the prognosis were analyzed. Results Univariate analysis showed that age, immediate NIHSS score after treatment, atrial fibrillation history, BMI, hypertension, hyperlipidemia and so on were the influencing factors of poor prognosis （P〈0.05）. Logistic regression analysis showed that age of 75 years old or older, immediate NIHSS score after treatment higher than 10 points, atrial fibrillation history and hypertension were the independent risk factors of poor prognosis （P〈0.05）. Conclusions Advanced age, immediate NIHSS score after treatment higher than 10 points, atrial fibrillation history and hypertension are the independent risk factors leading to poor prognosis of intravenous thrombolysis combined with endovascular intervention.