苯磺酸氨氯地平和苯磺酸左旋氨氯地平治疗高血压的效果

Effects of amlodipine besylate and levoamlodipine besylate in the treatment of hypertension

目的分析并探讨苯磺酸氨氯地平和苯磺酸左旋氨氯地平治疗高血压的效果。方法选择本院2014年11月至2017年11月收治的246例高血压患者为研究对象。依据患者入院时间划分为A组和B组,各123例。A组给予苯磺酸左旋氨氯地平治疗,B组给予苯磺酸氨氯地平治疗。比较两组患者的血压情况、临床疗效与不良反应发生情况。结果治疗后,A组的DBP、SBP、动态DBP、动态SBP水平均低于B组(P<0.05);两组患者的24 h SBP、24 h DBP水平与不良反应总发生率比较,差异无统计学意义(P>0.05)。A组患者的治疗总有效率高于B组(P<0.05)。结论为高血压患者行苯磺酸左旋氨氯地平治疗可显著降低其血压水平,临床疗效理想,且不良反应少。

Objective To analyze and discuss the effects of amlodip ine besylate and levoamlodipine besylate in the treatment of hypertension. Methods A total of 246 patients with hypertension admitted in our hospital from November 2014 to November 2017 were selected as the study objects. According to the patient＇s admission time, the patients were divided into group A and group B, with 123 cases in each group. The group A was treated with levoamlodipine besylate, and the group B was treated with amlodipine besylate. The condition of blood pressure, clinical effects and adverse reactions were compared between the two groups. Results After treatment, the levels of DBP, SBP, the dynamic SBP and the dynamic DBP of the group A were lower than those of the group B（P〈0.05）. There were no significant differences in 24 h SBP, 24 h DBP levels and total incidences of the adverse reactions between the two groups（P〉0.05）. The total effective rate of treatment in the group A was higher than that in the group B（P〈0.05）. Conclusion Levoamlodipine besylate in the treatment of hypertension can significantly reduce the level of blood pressure, with ideal clinical effect and less adverse reaction.