血常规、CRP和PCT在一般人群感染性疾病早期诊断中的临床价值

Clinical value of blood routine, CRP and PCT in early diagnosis of infectious diseases in general population

目的探讨在一般人群感染性疾病早期诊断中运用血常规、CRP和PCT的临床价值。方法选择本科室2016年10月至2017年10月一般人群感染性疾病120例患者(感染组)和80例健康体检人员(健康组)实施研究,所有人员均实施血常规、CRP、PCT检查,分析比较不同人员的检测结果差异性及各指标检测阳性率状况。结果细菌感染组、病毒感染组和健康组的WBC、CRP、PCT检测水平呈逐渐下降趋势(P<0.05)。WBC+CRP+PCT联合检查的阳性率较WBC、CRP、PCT单独检测均略有升高。细菌感染患者WBC+CRP+PCT联合检查阳性率较病毒感染患者、健康组人员更高(P<0.05)。病毒感染患者WBC+CRP+PCT联合检查阳性率与健康组人员无明显差异(P>0.05)。结论在一般人群感染性疾病早期诊断中运用血常规、CRP、PCT效果显著,且联合诊断可进一步提升诊断效果。

Objective To investigate the clinical value of blood routine, CRP and PCT in the early diagnosis of infectious diseases in general population. Methods There were 120 patients in the general population of infectious diseases in our department from October 2016 to October 2017（infection group） and 80 cases of healthy physical examination people（healthy group） as the subjects. All the personnel examinated blood routine, CRP and PCT, and the test results of different personnel and difference of each index were analyzed and compared. Results The WBC, CRP, PCT levels of the virus infection group, the bacterial infection group and healthy group gradually decreased（P〈0.05）. The positive rate of the WBC ＋CRP ＋PCT joint examination were slightly higher than WBC, CRP, PCT individually tested. The positive rate of WBC ＋CRP ＋PCT in patients with joint examination of the virus infection group was higher than those of objects in the bacterial infection group and healthy group（P〈0.05）. There was no difference in the positive rate of WBC ＋CRP ＋PCT between the bacterial infection group and the healthy group（P〈0.05）. Conclusion The effect of blood routine, CRP and PCT on the early diagnosis of infectious diseases in the general population is significant, and the combined diagnosis can further improve the diagnostic effect.