老年肺部感染患者采用低相对分子质量肝素预防下肢深静脉血栓形成的效果

Effect of low Molecular Weight Heparin on Prevention of deep Venous Thrombosis in Elderly Patients with Pulmonary Infection

目的观察低相对分子质量肝素(LWMH)对老年肺部感染患者下肢深静脉血栓形成(DVT)的预防作用。方法选择2014.12至2017.3我院ICU收治的78例肺部感染患者,分为LWMH组(41例)与对照组(37例);对比两组的DVT发生率、血气指标、凝血与纤溶指标、炎性介质水平。结果对照组下肢DVT发生率为20.05%,LWMH组为7.31%(P<0.05);对照组的TNF-α、D-D水平高于LWMH组,LWMH组的aPTT、PT水平上调(P<0.05);对照组的PaCO_2高于LWMH组,FaO_2、SaO_2、PaO_2低于LWMH组,(P<0.05)。结论 LWMH可有效地降低老年肺部感染患者DVT的发生率。

Objective To observe the effect of low molecular weight heparin （LWMH） on the formation of deep venous thrombosis in patients with pulmonary infection in the elderly （DVT）. Methods The preventive effect of 2014. 12 to 2017.3 ICU in our hospital were 78 cases of patients with pulmonary infection were divided into LWMH group（41 cases）and control group （37 cases） ;incidence comparing the two groups of DVT blood gas index, blood coagulation and fibrinolysis, levels of inflammatory mediators. Results The control group incidence rate of DVT was 20. 05% ,7.31% in LWMH group（ P 〈 0. 05 ） ;control group TNF-α, D- D level is higher than that LWMH group, LWMH group, aPTT, PT level increased （ P 〈 0. 05 ） ; the control group of PaCO2 group was higher than that of LWMH, FaO2, SaO2, PaO2 lower than that of LWMH group （P 〈0.05 ）. Conclusion LWMH can effectively reduce the incidence of DVT in patients with pulmonary infection in the elderly.