原发性硬化性胆管炎患者肝移植的研究进展

Advances in liver transplantation for patients with primary sclerosing cholangitis

原发性硬化性胆管炎（PSC）作为一种常见的自身免疫性肝脏疾病，其治疗方式的多样性广受各国学者关注。而肝移植（LT）作为其终末期治疗的最佳方法，由于患者伴发疾病、术后并发症等原因大大限制了其在临床的广泛应用。若能于移植早期行相关评估、干预，则可极大降低伴发疾病风险，减少术后并发症的发生。本文主要对PSC患者LT指征、时机及相关伴发疾病处理、术后并发症等方面的研究现状予以综述。

Primary sclerosing cholangitis （ PSC ） is a common autoimmune liver disease, and the diversity of its treatment methods has been hotly discussed by scholars in various countries. As the best treatment, end-stage liver transplantation （LT）, due to the related diseases, such as postoperative complications greatly limits its wide application in clinical practice. Early assessment and intervention can reduce the risk of concom- itant disease and reduce the occurrence of postoperative complications. In this paper, the status of LT indications, timing and related disease management, postoperative complications and other aspects of PSC patients were reviewed.