胃肠道恶性肿瘤免疫治疗的研究现状与展望

Research progress and perspective of immunotherapy for gastrointestinal malignant tumors

随着肿瘤学、免疫学以及分子生物学等相关学科的迅速发展和交叉渗透，肿瘤免疫治疗的研究突飞猛进。免疫治疗成为继手术、放射治疗和化学治疗之后又一种重要的治疗胃肠道恶性肿瘤的手段。新型的免疫治疗技术得到迅速发展，为晚期胃肠道恶性肿瘤患者带来新的希望。化学治疗联合免疫治疗有望成为晚期胃肠道恶性肿瘤治疗的新模式。同时如何客观评价免疫治疗疗效也成为研究热点。

With the rapid development and crosspenetration of ontology, immunology and molecu- lar biology, the research of tumor immunotherapy has made great progress, hnmunotherapy has become an important means for the treatment of gastrointestinal malignancies following surgery, radiotherapy and chem- otherapy. The novel immunotherapy technology has been developed rapidly and brings new hope for patients with advanced gastrointestinal malignant tumor. Chemotherapy combined with immunotherapy is expeeteJ to be a new model for the treatment of advanced gastrointestinal malignant tumors. At the same time, objectively evaluating the therapeutic effect of immunotherapy has also become a hot spot of research.