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不同剂量瑞芬太尼复合丙泊酚靶控输注麻醉在老年手术患者中的应用效果比较研究 被引量:2

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摘要 目的比较不同瑞芬太尼剂量复合丙泊酚靶控输注麻醉在老年手术患者中的应用效果。方法选取巴州人民医院2015年1月—2017年1月收治的老年手术患者160例,随机分为对照组和观察组,各80例。患者均予以丙泊酚,对照组患者瑞芬太尼初始靶效应室浓度为4 ng/ml,观察组患者瑞芬太尼初始靶效应室浓度为2.5 ng/ml。比较两组患者意识消失时间、自主呼吸恢复时间、呼之睁眼时间、拔管时间及不同时间(意识消失后、气管插管时、拔管后2 min、手术开始10 min、手术结束前5 min)收缩压、舒张压水平。结果观察组患者意识消失时间、自主呼吸恢复时间、呼之睁眼时间及拔管时间短于对照组(P<0.05)。观察组患者意识消失后、气管插管时、插管后2min、手术开始10 min、手术结束前5 min的收缩压、舒张压水平优于对照组(P<0.05)。结论采用瑞芬太尼2.5ng/ml初始靶效应浓度复合丙泊酚麻醉应用于老年手术患者中更为合理,其可更有效维持血流动力学稳定,缩短患者自主呼吸恢复、呼之睁眼、拔管时间。
作者 范春兰 袁辉
出处 《临床合理用药杂志》 2018年第9期79-80,共2页 Chinese Journal of Clinical Rational Drug Use
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