摘要
残胃癌与原发胃癌的预后是否相同.目前存在一定争议。考虑到残胃癌在诱发因素、治疗策略及淋巴结转移特点等方面与原发胃癌存在明显差异,因此.需将其与原发胃癌区别对待。整体而言,原发疾病性质、残胃癌的发生部位、组织学分型、浸润深度、淋巴结转移、远处转移等临床病理因素以及治疗方式的选择、原发灶切除范围、淋巴结清扫范围等治疗因素影响残胃癌的预后。因目前关于残胃癌的研究样本量均相对有限,未来仍需大样本研究予以进一步验证。
Gastric stump cancer was first defined as cancer occurring in the remnant stomach 5 years or later following distal subtotal gastrectomy of a benign stomach tumor. This definition was expanded to include malignant gastric cancer recurrence following distal gastrectomy and heterochronous gastric adenocareinoma. Evidence regardingwhether patients with gastric stump cancer had the same prognosis as those with primary gastric cancer has been inconsistent. Nonetheless, conidering the notable differences regarding risk factors, treatment strategies, and lymph node metastasis status, gastric stump cancer should be differentiated from primary tomach cancer. Overall, the prognosis of gastric stump cancer is influenced by clinicopathological characterislics such as primary tumor features, location of gastric stamp cancer, histological type, invasion depth, lymph node metastasis, and distant metastasis, as well as treatnLent factors such as treatment strategy, dissection range, and lymph node resection range. In previous studies on gastric sturp cancer, the sample size was limited, and future studies with larger sample size are needed to further validate the prognostic factors of gastric stump cancer.
作者
李子禹
王胤奎
季加孚
Li Ziyu;Wang Yinkui;Ji Jiafu(Department of Gastrointestinal Cancer Center, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing 100142, China)
出处
《中华胃肠外科杂志》
CAS
CSCD
北大核心
2018年第5期491-497,共7页
Chinese Journal of Gastrointestinal Surgery
基金
北京市医院管理局重点医学专业发展计划胃癌专业(ZYLX201701)
科技部支撑计划(2014BA109802)
关键词
残胃癌
预后
影响因素
Gastric stump cancer
Prognostic
Factors