并发冠状动脉损害的川崎病发热持续时间观察

Observation on fever duration of Kawasaki disease complicated with coronary artery lesions

目的对儿童川崎病(KD)发热持续时间与冠状动脉损害进行临床研究。方法选择2013年1月-2014年6月间茂名市电白区人民医院收治的42例KD患儿,所有患儿入院后均接受心脏彩超检查,观察是否存在冠状动脉病变,按照检查结果划分为观察组10例与对照组32例,观察组为KD合并有冠状动脉病变患儿,对照组KD无合并冠状动脉病变患儿,将两组患儿发热持续时间进行比较。结果观察组入院后体温在第4天恢复正常为8例(80.00%),>7 d恢复正常为2例(20.00%);对照组体温在治疗后第2天恢复正常者为18例(56.25%),第3天恢复正常为14例(43.75%)。观察组10例患儿中,冠状动脉扩张4例(40.00%),冠状动脉瘤6例(60.00%)。结论通过早期诊断、积极治疗,缩短KD患儿发热时间,有助于减少KD患儿冠状动脉病变的发生。

Objective To study fever duration and coronary artery lesion damage of Kawasaki disease （KD） in children. Methods 42 cases of KD from January 2013 to June 2014 in Maoming Dianbai District People＇s Hospital were selected, all patients received cardiac ultrasound examination to observe the presence of coronary artery disease, and were divided into the observation group with 10 cases combined with coronary artery lesions and control group with 32 cases without coronary artery lesions, according to the examination results. The fever duration between the two groups were compared. Results The body temperature of 8 cases （80.00%） in the observation group returned to normal at fourth day after admission, 2 cases （20.00%） returned to normal for more than 7 days after admission. In the control group, the body temperature of 18 cases （56.25%） recovered to normal at second day after treatment, 14 cases （43.75%） recovered to normal at third day. Among the 10 patients in the observation group, the type of coronary lesion were coronary artery dilatation with 4 cases （40.00%）, and coronary artery aneurysm with 6 cases （60.00%）. Conclusion Early diagnosis and active treatment, shorten the duration of fever in children with KD can reduce the incidence of coronary artery disease.