母亲过敏和环境暴露对免疫成熟的影响

Effect of maternal allergy and environmental exposure on immune maturation

近年来,母亲过敏和环境暴露对免疫成熟的影响受到广泛关注。出生前后是免疫成熟的关键时期,过敏母亲后代脐带血中免疫成分发生改变,其具体机制尚在研究之中。同时,母亲环境暴露可能对胎儿免疫功能产生长久的正面或负面影响,该综述总结了近些年出现的暴露因素及其对免疫成熟的影响。

In recent years, the effects of maternal allergy and environmental exposure on immune maturation have attracted a lot of attention. The period before and after birth is key to immune maturation, exchange of maternal allergic immune components in cord blood, but the exact mechanism is unclear. Meanwhile, environmental exposure may have positive or negative effects on fetal immune function. This article summarizes the exposure factors and their effects on immune maturation.