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非布司他临床应用及不良反应 被引量:2

His clinical application and adverse reactions
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摘要 非布司他作为痛风、高尿酸血症临床治疗中最常用的降尿酸药物,疗效明确、耐受性较好,但存在如肝功能异常、头痛、恶心、呕吐及皮疹等不良反应。为了更好地在临床中治疗痛风和高尿酸血症,本文就非布司他的临床应用及不良反应加以阐述。非布司他可累及多个系统/器官,主要包含皮肤及附件损害、肝功能损伤、心血管系统不良反应等,且临床表现多样,应加强用药监护,预防不良反应发生。
作者 刘小庆
出处 《实用妇科内分泌电子杂志》 2017年第33期163-163,165,共2页 Electronic Journal of Practical Gynecological Endocrinology
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  • 1Becker MA, Schumacher HR Jr, Wortmann RL, et al. Febuxostat compared with allopurinol in patients with hyperuricemia and gout [J]. N Engl J Med, 2005, 353(23) : 2450-2461.
  • 2Becker MA, Macdonald PA, Hunt BJ, et al. Diabetes and gout: efficacy and safety of febuxostat and allopurinol[J]. Diabetes Obes Metab, 2013, 15(11): 1049-1055.
  • 3Stamp LK, Jordan S. The challenges of gout management in the elderly [J]. Drugs Aging, 2011, 28(8) : 591-603.
  • 4Wells AF, MacDonald PA, Chefo S, et al. African American pa- tients with gout: efficacy and safety of febuxostat vs allopurinol[J].BMC Musculoskelet Disord, 2012, 13: 13-15.
  • 5Chohan S, Becker MA, MacDonald PA, et al. Women with gout: efficacy and safety of uratc-lowering with fehuxostat and allopurinol [ J ]. Arthritis Care Res (Hoboken) , 2012, 64 (2) : 256-261.
  • 6Hair PI, McCormack PL, Keating GM. Febuxostat [J]. Drugs, 2008, 68(13) : 1865-1874.
  • 7Abeles AM. Febuxostat hypersensitivity [ J]. J Rheumatol, 2012, 39(3) : 659.
  • 8Chohan S. Safety and efficacy of febuxostat treatment in subjects with gout and severe allopurinol adverse reactions [J].J Rheuma- tol, 2011, 38(9) : 1957-1959.
  • 9Becker MA, Schumacher HR, Espinoza LR, et al. The urate-low- ering efficacy and safety of febuxostat in the treatment of the hype- ruricemia of gout : the CONFIRMS trial [ J]. Arthritis Res Ther, 2010, 12(2): R63.
  • 10Gandhi PK, Gentry WM, Bottorff MR. Cardiovascular thromboem- bolic events associated with febuxostat : investigation of cases from the FDA adverse event reporting system database [ J ]. Semin Arthritis Rheum, 2013,42(6) : 562-566.

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