摘要
目的评估夫西地酸联合维A酸乳膏治疗中度痤疮临床疗效。方法将146例中度痤疮患者随机分成3组,治疗组予夫西地酸联合维A酸乳膏治疗,对照组A予夫西地酸乳膏治疗,对照组B予维A酸乳膏治疗,治疗4周和6周分别判定疗效。疗程结束对患者进行满意度评价。结果治疗4周,治疗组、对照组A和对照组B有效率分别为70.0%、44.0%和40.0%。治疗组的有效率高于对照组A和对照组B(P<0.05)。治疗6周,治疗组、对照组A和对照组B有效率分别为82.0%、56.0%和48.0%。治疗组的有效率高于对照组A和对照组B(P<0.05)。治疗组满意度评分优于对照组A和对照组B(P<0.05)。结论夫西地酸联合维A酸乳膏治疗中度痤疮疗效较好,不良反应少,患者满意度高。
Objective To assess the therapeutic efect of the combination of fusidic acid and tretinoin cream in patients with moderate acne. Methods One hundred and forty-six patients with moderate acne were randomly divided into three groups. Patients in the treatment group were treated withfusidic acid and tretinoin cream, control group A were treated with fusidic acid and control group B were treated with tretinoin cream. The efects were evaluatedat 4 weeks and 6 weeks. Patient satisfaction surveys were used in the final. Results The effective rate at 4 weeks was better for the treatment group compared with control group A and B(70.0% vs . 44.0% vs. 40.0%, P 〈 0.05). The efective rate at 6 weeks was better for the treatment group (82.0% vs. 56.0% vs. 48.0%, P 〈 0.05). The score in patient satisfaction was higher in the treatment group than control group A and B (P 〈 0.05). Conclusion The combination of fusidic acid and tretinoin cream is efective and safe in treating moderate acne,and achieves a highlevel of patient satisfaction.
作者
卢珍玲
姜晓勇
王德辉
LU Zhenling;JIANG Xiaoyong;WANG Dehui(Dermatology Department, Zhongshan Hospital Affiliated to Xiamen University, Xiamen Fujian 361004, China)
出处
《中国卫生标准管理》
2018年第9期75-77,共3页
China Health Standard Management