期刊文献+

夫西地酸联合维A酸乳膏治疗中度痤疮的临床研究 被引量:1

Clinical Study of the Combination of Fusidic Acid and Tretinoin Cream in Patients With Moderate Acne
下载PDF
导出
摘要 目的评估夫西地酸联合维A酸乳膏治疗中度痤疮临床疗效。方法将146例中度痤疮患者随机分成3组,治疗组予夫西地酸联合维A酸乳膏治疗,对照组A予夫西地酸乳膏治疗,对照组B予维A酸乳膏治疗,治疗4周和6周分别判定疗效。疗程结束对患者进行满意度评价。结果治疗4周,治疗组、对照组A和对照组B有效率分别为70.0%、44.0%和40.0%。治疗组的有效率高于对照组A和对照组B(P<0.05)。治疗6周,治疗组、对照组A和对照组B有效率分别为82.0%、56.0%和48.0%。治疗组的有效率高于对照组A和对照组B(P<0.05)。治疗组满意度评分优于对照组A和对照组B(P<0.05)。结论夫西地酸联合维A酸乳膏治疗中度痤疮疗效较好,不良反应少,患者满意度高。 Objective To assess the therapeutic efect of the combination of fusidic acid and tretinoin cream in patients with moderate acne. Methods One hundred and forty-six patients with moderate acne were randomly divided into three groups. Patients in the treatment group were treated withfusidic acid and tretinoin cream, control group A were treated with fusidic acid and control group B were treated with tretinoin cream. The efects were evaluatedat 4 weeks and 6 weeks. Patient satisfaction surveys were used in the final. Results The effective rate at 4 weeks was better for the treatment group compared with control group A and B(70.0% vs . 44.0% vs. 40.0%, P 〈 0.05). The efective rate at 6 weeks was better for the treatment group (82.0% vs. 56.0% vs. 48.0%, P 〈 0.05). The score in patient satisfaction was higher in the treatment group than control group A and B (P 〈 0.05). Conclusion The combination of fusidic acid and tretinoin cream is efective and safe in treating moderate acne,and achieves a highlevel of patient satisfaction.
作者 卢珍玲 姜晓勇 王德辉 LU Zhenling;JIANG Xiaoyong;WANG Dehui(Dermatology Department, Zhongshan Hospital Affiliated to Xiamen University, Xiamen Fujian 361004, China)
出处 《中国卫生标准管理》 2018年第9期75-77,共3页 China Health Standard Management
关键词 痤疮 中度 夫西地酸 维A酸乳膏 acne moderate fusidic acid tretinoin cream
  • 相关文献

参考文献8

二级参考文献74

  • 1吴军,李颖,余志请,郑红,何威,黄海,何德春,唐天龙.0.1%维A酸霜治疗寻常痤疮临床疗效观察[J].西部医学,2005,17(4):374-374. 被引量:4
  • 2韦高,吴易.健康教育在痤疮治疗中的作用[J].广西医学,2005,27(9):1481-1482. 被引量:3
  • 3毕新岭,顾军,温海,章伟.夫西地酸乳膏治疗细菌性皮肤病的临床观察[J].中华皮肤科杂志,2006,39(9):546-546. 被引量:49
  • 4赵辨.中国临床皮肤病[M].南京:江苏科学技术出版社,2010:1498-1499.
  • 5徐高淳,缪水云.0.025%维A酸乳膏联合中药治疗寻常痤疮的临床疗效观察[J].中国中西医结合皮肤性病学杂志,2007,6(3):176-176. 被引量:3
  • 6Balkrishnan R, Kulkarni AS, Cayce K, et al. Predictors of healthcare outcomes and costs related to medication use in patients with aene in the United States[J]. Cuffs, 2006,77(4): 251-255.
  • 7Cook D, Krassas G, Huang T, et al. Aene- best practice man- agement[J]. Aust Faro Physician, 2010, 39(9): 656-660.
  • 8Dunn LK, O' Neill JL, Feldman SR. Ache in adolescents: qual- ity of life, self-esteem, mood, and psychological disorders[J]. Dermatol Online J, 2011, 17(1): 1.
  • 9Pawin H, Beylot C, Chivot M, et al. Physiopathology of acne vulgaris: recent data, new understanding of the treatments[J]. Eur J Dermatol, 2004, 14: 4-12.
  • 10Leyden JJ. A review of the use of combination therapies for the treatment of ache vulgaris[J]. J Am Acad Dermatol, 2003, 49 (Suppl.): S200-S210.

共引文献570

同被引文献3

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部