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连续收肌管阻滞联合浸润镇痛对全膝关节置换术后疼痛和应激反应的影响 被引量:7

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摘要 目的探讨连续收肌管阻滞联合关节周围浸润镇痛对全膝关节置换术后的疼痛和应激反应的影响。方法选择2016年2月至12月本院拟行单侧膝关节置换手术的患者60例,随机均分为2组:连续收肌管阻滞组(C组),连续收肌管阻滞联合关节周围浸润镇痛组(C+P组);术中行腰硬联合麻醉。记录术后6、12 h、1、2、3、5 d静息和活动疼痛视觉模拟评分;记录术前及术后1、2、3、5 d白细胞计数、血糖、C-反应蛋白(CRP)变化;记录术后补救性镇痛药用量及不良反应(如神经损伤、局麻药中毒等)情况。结果 C+P组在术后6、12 h、1、2 d静息VAS评分和术后6、12 h、1、2、3 d活动VAS评分明显低于C组,且差异有统计学意义(P<0.05);C+P组血糖和CRP水平在术后1、2、3d明显低于C组,差异有统计学意义(P<0.05)。C+P组额外镇痛药使用次数(0.30±0.18)明显低于C组(0.80±0.81)(P<0.05)。两组均无明显不良反应。结论连续收肌管阻滞联合关节周围浸润在膝关节置换术后镇痛效果更完善,疼痛应激反应下降,不良反应少。
出处 《中国医师杂志》 CAS 2018年第4期557-559,共3页 Journal of Chinese Physician
基金 国家自然科学基金青年项目(81501207)
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