摘要
To the Editor: Epidermal growth overexpressed in non-small cell factor receptor (EGFR) is lung cancer (NSCLC) and contains a tyrosine kinase inhibitor (TKI) domain which acts as an important therapeutic target. Previous studies have observed the efficacy of EGFR-TKIs in the most commonly targeted exon mutations (19 and 21). This study was to investigat the pathologic features of uncommon EGFR mutations and the clinical efficacies of EGFR-TKIs treatment.
To the Editor: Epidermal growth overexpressed in non-small cell factor receptor (EGFR) is lung cancer (NSCLC) and contains a tyrosine kinase inhibitor (TKI) domain which acts as an important therapeutic target. Previous studies have observed the efficacy of EGFR-TKIs in the most commonly targeted exon mutations (19 and 21). This study was to investigat the pathologic features of uncommon EGFR mutations and the clinical efficacies of EGFR-TKIs treatment.