通心络联合阿托伐他汀治疗冠心病不稳定型心绞痛的效果观察

Observation on the Effect of Tongxinluo Combined with Atorvastatin in Treating Unstable Angina Pectoris of Coronary Heart Disease

目的探析冠心病不稳定型心绞痛患者接受通心络、阿托伐他汀联合治疗的临床效果。方法选取2017年1月至6月在本院接受诊治冠心病不稳定型心绞痛患者为研究对象,从中抽取100例并编号,随机数字表将其分为用冠心病心绞痛西医对症治疗的常规组(n=50),西药治疗基础上应用通心络、阿托伐他汀治疗的联合组(n=50)。在3个疗程后对患者临床疗效、临床症状、体征变化进行记录比较。结果联合组患者病情干预有效率明显高于常规组(P<0.05);联合组治疗后经检测各项相关临床指标改善情况明显优于常规组(P<0.05);联合组心绞痛发作次数、发作持续时间及硝酸甘油用量等情况明显优于常规组(P<0.05)。结论冠心病不稳定型心绞痛患者在接受治疗干预时,可将通心络、阿托伐他汀联合方案作为主要手段,效果突出且对相关指标有调整作用,值得推广。

Objective To investigate the clinical effect of combined treatment of Tongxinluo and atorvastatin in patients with unstable angina pectoris of coronary heart disease. Methods From January 2017 to June in our hospital for diagnosis and treatment of coronary heart disease in patients with unstable angina as the research object, extracted from 100 cases and number, were randomly divided into routine treatment group with angina pectoris of coronary heart disease（n=50）, the western medicine combined group Tongxinluo and atorvastatin treatment based on Western Medicine the（n=50）. After 3 courses of treatment, the clinical efficacy, clinical symptoms and signs of the patients were recorded and compared. Results The effective rate of intervention was significantly higher in the combined group than in the conventional group（P〈0.05）; the combined group indexes of heart function, left ventricular ejection fraction（LVEF）, left ventricular end diastolic diameter（LVEDD）, left ventricular posterior wall thickness（LVPWD） was significantly better than the conventional group（P〈0.05）; group angina attack frequency, duration and dosage of nitroglycerin was significantly better than the conventional group（P〈0.05）. Conclusion Tongxinluo combined with atorvastatin in patients with unstable angina pectoris of coronary heart disease has a positive effect on the disease, and it is worthy to be widely promoted in the clinical field.