研究血液病患者疑难交叉配血原因

To Study the Blood of Patients with Difficult Cross-matching Blood Causes

目的研究讨论血液病患者疑难交叉配血原因。方法抽取血库中2015年至2017年采集的疑难交叉配血标本进行血型鉴定、不规则抗体筛查和鉴定等,并统计分析数据,探讨血液病患者疑难交叉配血原因。结果血液病患者凝聚胺交叉配血不合以不规则抗体阳性是最为多见的因素,占比80.00%(12/15),而不规则抗体阳性又主要表现为同种抗体产生,占比83.33%(10/12),其中Rh系统抗体占比70.00%(7/10);输血5次及以下的血液病患者检出不规则抗体的几率明显高于输血5次以上患者。结论血液病患者在进行输血之前,对不规则抗体进行筛查十分重要,能够促进输血质量及输血安全有效提高。

Objective To study and discuss the causes of difficult cross-matching of blood diseases. Methods Blood samples from blood bank were collected for blood type identification, screening and identification of irregular antibodies, and the data were analyzed statistically to find out the reasons for difficult blood cross matching in patients with blood diseases. Results Hepatic blood coagulation cross-incompatible with irregular antibody positive is the most common factor, accounting for 80.00%（12/15）, and irregular antibody positive and mainly for the same antibody, accounting for 83.33 %（10/12）, of which Rh antibody accounted for 70.00%（7/10）. The incidence of irregular antibodies in hematological diseases with blood transfusion less than 5 times was significantly higher than those with blood transfusion more than 5 times. Conclusion It is very important for patients with hematological diseases to screen for irregular antibodies before blood transfusion, which can promote the quality of blood transfusion and improve the safety of blood transfusion.