介入治疗对冠心病中医证型影响的临床研究

Clinical study on the change of traditional Chinese medicine syndrome in patients with coronary heart disease before and after intervention treatment

[目的]研究介入治疗对中医证型的影响。[方法]选择经冠脉造影术确诊冠心病并行经皮穿刺腔内冠状动脉成形术及支架植入术(PTCA+STENT)治疗的患者30例,分析治疗前后症状及证型变化规律。[结果]治疗后与治疗前相比心血瘀阻证、阴寒凝滞证减少,痰浊痹阻证未见明显改变,气阴两虚证、心肾阳虚证较前增多。治疗后与治疗前相比胸闷、胸痛等症明显减少,脘腹胀满、乏力等症未见明显改变。[结论]经皮冠状动脉介入治疗(PCI)术前后患者"标实"与"本虚"偏重不同,但"本虚标实"的基本病机不变。

[Objective] To study the effect of interventional therapy on traditional Chinese medicine syndromes. [Methods] Thirty patients with coronary artery disease underwent PTCA＋STENT were diagnosed by coronary angiography. The changes of symptoms and signs were analyzed before and after treatment. [Results] After treatment, blood stasis and cold coagulation reduced than that before treatment, and phlegm no obvious change. Qi and yin Deficiency, heart and kidney yang deficiency was increased. After treatment compared with before treatment such as chest tightness, chest pain embolism was significantly reduced before, abdominal distention, tired and fatigue and other symptoms and signs no significant changed. [Conclusion] It is different from the degree of ＂deficiency in root＂ and＂excess in superficiality＂ in patients before and after PCI. But it failed to change the basic pathogenesis of patients with ＂deficiency in root and excess in superficiality＂.