阿奇霉素治疗小儿呼吸道肺炎支原体感染临床疗效分析

Analysis of clinical effect of azithromycin on mycoplasma pneumoniae infection in children

目的:探讨呼吸道肺炎支原体感染的患儿给予阿奇霉素口服治疗的效果和安全性。方法:选取某院收治的52例呼吸道肺炎支原体感染的患儿为观察对象,将其随机分为治疗组26例和对照组26例,治疗组给予口服阿奇霉素治疗,对照组实施红霉素治疗,分析比较2组患儿的临床治疗效果、不良反应发生率及症状体征消失时间等。结果:治疗后与对照组比较,治疗组临床疗效较好,差异有统计学意义(P<0.05);对照组不良反应发生率较治疗组高,差异有统计学意义(P<0.05);治疗组患儿发热、咳嗽、咳痰、干湿啰音消失时间较对照组短,2组比较差异有统计学意义(P<0.05)。结论:阿奇霉素治疗小儿呼吸道肺炎支原体感染能够快速缓解患儿的症状,提高治疗效果,且安全性好,具有较高的临床应用价值。

Objective ： To analyze the efficacy and safety of azithromycin in treatment of children with mycoplasma pneumoniae infection. Methods ：52 cases of children in a hospital with mycoplasma pneumoniae infection were selected and randomly divided into a treatment group and a control group, 26 cases in each. The treatment group was given oral azithromycin treatment, while the control group received erythromycin treatment. Clinical effect, adverse reaction and symptom disappearing time of the two groups were analyzed and compared. Results ： After the treatment, the clinical effect of the treatment group was superior to the control group, the difference being statistically significant（ P 〈0.05 ）. The incidence of adverse reaction in the control group was statistically higher than that in the treatment group （ P 〈 0.05 ）. Symptoms and signs of tever, cough, expectoration, dry and wet rales disappeared taster in the treatment group of than in the control group. The difference was of significance （ P 〈 0.05 ）. Conclusion ： The application of azithromycin in treatment of mycoplasma pneumoniae infection can significantly improve the treatment effect and quickly relieve symptoms. It is safe and can improve patients satistaction. It is worthy of further clinical promotion.