尤文肉瘤肿瘤家族(ESFT)临床循证诊疗指南

Guideline for clinical evidence-based diagnosis and treatment of Ewing sarcoma family tumor(ESFT)

尤文肉瘤是常见的原发恶性骨肿瘤,严重危害青少年的身体健康。通过规范的化疗、手术及放疗,很多患者可达到痊愈,但不当的诊疗过程可能造成严重的不良后果。中国医师协会骨科医师分会骨肿瘤专业委员会依据循证医学方法制定了《尤文肉瘤肿瘤家族(ESFT)临床循证诊疗指南》,就诊断流程、化疗、放疗、不同部位的手术方式及挽救性治疗等临床问题进行总结,依据文献证据等级给出相应的推荐等级。旨在为骨肿瘤医师的临床诊疗提供最佳的、有效的意见参考,从而使患者达到最佳的治疗效果。本指南仅为学术性指导意见,具体实施时必须依据患者的个体医疗情况而定。

Ewing sarcoma family tumors （ESFTs） are common primary malignancies of the bone and severely jeopardize teenagers＇ health. Standardized multi-modality treatment including chemotherapy, surgery and radiotherapy can achieve cure of disease for many patients, while improper treatments could lead to severe consequences. The Musculoskeletal Tumor Society from Chinese Association of Orthopaedic Surgeons proposes the ＂Guideline for clinical evidence-based diagnosis and treatment of Ewing sarcoma family tumor （ESFT）＂. This guideline addresses several clinical problems （e.g. diagnostic process, chemotherapy, radiotherapy, surgical options for lesions of different locations, and salvage treatments） and provides recommendations with categories of evidence and consensus. The aim of the guideline is to provide the most effective references for practitioners of oncologic orthopaedics in order to achieve ideal outcomes for patients. But this guideline provides only academic recommendations and should be adapted to individualized treatments during clinical practice.